Lab-Grown Embryo Research is proven to modify treatment
According to many studies, one in three pregnancies lead to premature birth, and one in 33 babies born have a birth defect because the embryo forms incorrectly in the womb. Studying how the embryo develops can help us find ways to reduce these numbers. In 2022, we will see advances in this research thanks to gas - based structures, similar to laboratory - grown embryos.
Stem cells offer a powerful way to study the early development of the embryo. They can be grown in the lab in large numbers and can be pushed towards a wide variety of cell types, including brain, blood, bone and muscle.
Recently, several researchers have discovered ways to bind stem cells together in small 3D balls of cells, which enable the formation of small embryo-like structures. These are basic right now - the structures can be variable, they are inefficient in creation and they cannot develop much more. Next year, we are likely to see improvements, with more advanced embryo-like structures made of stem cells. And we also tend to see scientists using these models to study specific problems, such as how the embryo enters the uterus, how organs begin to develop or how the embryo makes sure cells are in the right places.
Such a study has traditionally been difficult to perform with human embryos. Parents using in vitro fertilization are able to provide the extra primates, but regulation (maintained internationally and enshrined in UK law) prohibits researchers have been cultivating them for more than 14 days. This makes it impossible to study the development of the human embryo exactly as it changes from a group of cells to a structure with a basic group organization - when it is between two and four weeks old. The International Association for Stem Cell Research, which represents researchers in this field, has called for a public debate on whether this boundary should be changed. He suggests that human embryo culture should be expanded on a case-by-case basis. It remains to be seen how regulatory bodies will deal with this.
In the meantime, gas-like models may reduce some of the need to use “real” human embryos at all. They allow researchers to conduct detailed studies of prognostic development, seeing how they react when a gene is turned on, for example, or when exposed to dangerous chemicals. Because they are made with stem cells, they could be generated by taking blood or skin samples from patients with birth defects themselves and returning on the clock to a similar state. the embryo. This may help us to determine how the deficiency occurred, and perhaps even take steps to reduce the incidence of such disorders in the future.
The development of embryo-like models raises many new ethical questions. In addition to the ability to move down a slippery slope toward cloning, gas - based embryo models begin to scour the line between what we see as humans or not. Is an early-stage human embryo, when there is only a small group of 16 cells, more valuable if it comes from the union of sperm and egg? Or is it the same as coming from the lab from gas cells? Should the moral status applied in human embryos apply to groups of cells as well, even in arrangements that may simply mirror elements of embryo development?
As we push further towards models that may alleviate the destructive situations we face at the beginning of our lives, we will also be challenged as a society to ask big questions, taking the lead. -into the basic question of what it means to be human.
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